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December 12.2025
3 Minutes Read

Why Uterine Fibroids Could Significantly Increase Your Heart Disease Risk

3D heart rendering showing anatomical highlights linked to heart disease risk.

Understanding the Link: Uterine Fibroids and Cardiac Health

New research highlights an alarming connection between uterine fibroids and a significantly increased risk of cardiovascular disease among women. A recent study published in the Journal of the American Heart Association revealed that women diagnosed with uterine fibroids face an over 80% greater risk of long-term cardiac issues compared to those without fibroids. Interestingly, this heightened risk persists across various ages and ethnicities but is particularly pronounced in women under 40 years old.

The Impact of Uterine Fibroids

Uterine fibroids are benign tumors made up of muscle tissue found within the uterus, affecting a substantial number of women—estimated to be around 20% to as high as 80% before reaching the age of 50. Despite their prevalence, many women remain asymptomatic and largely uninformed about the potential health risks associated with fibroids. Research indicates that understanding this connection can prompt necessary medical discussions regarding heart health alongside fibroid diagnosis.

Research Findings

Researchers examined a comprehensive dataset involving over 2.7 million American women, out of which approximately 450,000 were diagnosed with fibroids. The scope of the study spanned from 2000 to 2022, allowing for a robust analysis of the correlation between uterine fibroids and major cardiovascular events, including coronary artery disease, cerebrovascular disease, and peripheral artery disease. Results indicated that more than 5% of women with fibroids experienced cardiovascular events, compared to just 3% of their counterparts without fibroids. The risk surged alarmingly among young women, with those under 40 presenting a staggering 251% increased risk of cardiovascular complications.

The Biological Mechanism Behind the Link

Experts suggest that the biological pathways contributing to both fibroid development and cardiovascular disease might overlap, involving factors such as inflammation and vascular dysfunction. Julia D. DiTosto, a Ph.D. candidate in epidemiology at the University of Pennsylvania, emphasizes the need for further exploration into these connections. She notes that these shared biological responses could be key to identifying and managing cardiovascular risk among women affected by fibroids.

Bridging the Gap: Healthcare Conversations

Given these findings, there’s a pressing call for healthcare providers to engage women in meaningful discussions regarding cardiovascular health, particularly when diagnosed with fibroids. Stacey E. Rosen, MD, of the American Heart Association, underscores the importance of holistic healthcare approaches, where women’s annual wellness visits can encompass assessments for cardiac health along with routine gynecological care.

Call to Action for Women’s Health Awareness

For women diagnosed with uterine fibroids, being proactive about heart health is crucial. This includes regular check-ups, open conversations with healthcare providers about risk factors for cardiovascular issues, and considering lifestyle modifications. Incorporating cardiovascular-friendly foods into daily diets (e.g., fruits, vegetables, nuts), staying physically active with tailored exercise regimens, and managing stress through mindfulness practices can create a protective effect on heart health.

What’s Next?

The link between uterine fibroids and cardiovascular risks is an emerging field of study requiring ongoing research to solidify these findings. Women affected by fibroids should remain informed, advocate for regular screenings, and maintain open dialogues with their healthcare providers. Future studies will be vital in further elucidating this relationship and ensuring that appropriate guidelines are established for managing risk in this patient population.

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